edX
edXCERTaIN: Observational Studies and Registries
37 studentsBEGINNER
edXRandomized trials set the research gold standard, but reality constrains their use: ethics, cost, and practicality often demand an alternative. Observational studies—leveraging existing data and real-world patient observation—offer richness that trials cannot. This course teaches you to interpret observational findings critically, apply analytic methods from SEER-Medicare linkages to survival analysis, and position health registries within comparative effectiveness research. Gain the literacy to evaluate non-experimental evidence and contribute to patient-centered outcomes research.
While randomized controlled trials are considered to be the "gold standard" in health research, they cannot always be performed, for ethical or practical reasons. Observational studies gather information from data that has already been collected, or by observing and measuring patients' changes in health status and their response to interventions outside of a clinical trial. In this course, you will learn to identify the characteristics of observational studies, to interpret the results of observational studies, and to describe the use of health registries in comparative effectiveness research (CER).
This course includes the following 11 lectures:
This course is intended for anyone interested in comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods.
This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.
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